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The Role Of The Dynorphin Κ Opioid System In The Reinforcing Effects Of Drugs Of Abuse

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0.03 mg/$

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This scientific review explores the role of the dynorphin–κ opioid system in modulating the reinforcing effects of addictive drugs. Evidence suggests bidirectional control where κ receptor activation attenuates initial drug rewards while also promoting negative affect states linked to compulsive use.

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